Effect of dexmedetomidine combined with the modified Trendelenburg position on intraocular pressure in patients undergoing robot-assisted laparoscopic surgery

A total of 160 patients scheduled for robot-assisted laparoscopic surgery were randomly assigned to four groups: the control group receiving normal saline and traditional positioning (NT group), the modified Trendelenburg position group (NM group), the dexmedetomidine group (DT group), and the dexmedetomidine-modified Trendelenburg position group (DM group). Intraocular pressure (IOP) was measured at baseline (T0), 2 minutes after anesthesia induction (T1), 0.5, 1.5, and 2.5 hours after CO2 pneumoperitoneum (T2, T3, T4), and 2 minutes after extubation (T5).

The incidence of adverse cardiovascular events, the utilization rate of vasoactive drugs, and complications related to intraocular hypertension (such as ocular swelling, ocular pain, nausea, vomiting, dizziness, and headache) within 24 hours after surgery were recorded.