Dimethylcurcumin alleviates inflammation by regulating Glycolipid Metabolism and Arachidonic Acid Metabolism

This study hypothesizes that dimethyl curcumin can exert anti-inflammatory effects by regulating the function of macrophages, reducing the level of reactive oxygen species (ROS), improving behavioral performance, and influencing the transcriptional expression and binding of inflammatory-related genes to target proteins. The data include statistics on the number of macrophage aggregation and migration in zebrafish in the control group, the copper sulfate inflammation model group, and the di-methyl turmeric treatment group; statistics on the content of reactive oxygen species; behavioral data processing; raw data and analysis data of the transcriptome; PCR verification data and molecular docking data.

These data indicate that di-methyl turmeric can exert anti-inflammatory effects through multiple pathways, including regulating macrophage function, eliminating reactive oxygen species, influencing the transcription of inflammation-related genes, and binding to key target proteins. This dataset provides a foundation for researchers in this field to deeply explore the anti-inflammatory mechanism of di-methyl turmeric, and offers data support for its subsequent drug development and clinical application.