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Data · dataset · 2022

RAW DATA

Listed in Teesside University Research Data Repository

This study found that after spinal cord injury, macrophages phagocytize myelin debris to form foamy macrophages, while microglia do not form foamy cells, which may be because microglia can effectively clear myelin debris in a relatively short time, whereas macrophages cannot.

Description

In addition, we found that ACAT1 did not mediate the formation of foamy macrophages after spinal cord injury, which was different from atherosclerosis.

This study demonstrates that microglia have a stronger ability to clear myelin debris than macrophages and may contribute to the development of novel therapeutic strategies to remove myelin debris more effectively, reduce inflammatory responses, promote remyelination, and accelerate functional recovery after spinal cord injury.

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Where it is published

Catalogue records · 1

Topics

From keywords
Earth & Environmental Science
Provenance · 1 source records, 6 field assertions
SourceKeyLast seenRaw
Teesside University Research Data Repositoryoai:data.mendeley.com/txygpjpzbj.116 h agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:earth-environmentalmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
descriptionsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/description
licensesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/rights
publication_datesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
titlesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/title