Data · dataset · 2021
Genome-wide association study identifies two novel susceptibility loci for trichilemmal cysts
Listed in Teesside University Research Data Repository
Trichilemmal cysts (TC), also known as pilar cysts, are keratin-filled, subepidermal nodules originating from the outer hair root sheath.
Description
Recently phospholipase C delta 1 has been suggested to play a critical role in the formation of TCs. However, it is unknown if other genes contribute to TC formation.
We conducted a genome-wide association study (GWAS) of 5,331 TC cases and 403,251 controls in a genetically British group. Our genome-wide scan revealed PLCD1, CLPTM1L, and TMED10|FOS as susceptibility loci for TCs. Additionally, we performed a follow-up GWAS on 2,806 epidermal inclusion cysts and 405,776 controls in the same population, without identifying any susceptibility loci.
Links
Where it is published
- DOI doi.org/10.17632/ktwhf64cxz.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Dermatology · Earth & Environmental Science · Life Sciences
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/ktwhf64cxz.1 | 19 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].anzsrc:field:320205 | mapping · researchdata tees ac uk | vocabulary-mapper@1.0.0 | keywords['Dermatology'] |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |