Liberal fluid resuscitation induces occult biventricular uncoupling and delayed multiorgan injury in hemorrhagic shock: evidence

Macrohemodynamic parameters: systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), stroke volume (SV), stroke volume variation (SVV), cardiac index (CI), right atrial pressure (RAP), pulmonary artery systolic pressure (sPAP), pulmonary capillary wedge pressure (PCWP), end‑tidal carbon dioxide partial pressure (ETCO₂), etc.2. Biventricular echocardiographic parameters: left ventricular ejection fraction (LVEF), fractional shortening (FS), left atrial volume (LA Vol), mitral valve E/A ratio, mitral valve deceleration time (MV Dec.

Time), mean tissue Doppler E/E’ ratio; right ventricular tricuspid annular plane systolic excursion (TAPSE), maximal tricuspid regurgitation pressure gradient (TR PGmax), right ventricular internal diastolic diameter (RVIDd), right ventricular tissue Doppler velocity (RV S‘), and the calculated TAPSE/sPAP ratio.3. Serum biochemical markers: alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), creatine kinase myocardial band (CK-MB), serum creatinine (Cr), blood urea nitrogen (BUN), BUN/creatinine ratio (BUN/Cr), total bilirubin (TBIL), measured at multiple time points (baseline, hemorrhage stages, resuscitation endpoints, and postoperative days 1, 2, 3, 7).All data have been anonymized and contain no individual animal identifiers.

The data files are in Excel format (.xlsx), including raw data tables and a data dictionary describing variable names, units, and measurement time points. This dataset can be used by other researchers for validation, secondary analysis, or systematic reviews, providing primary data support for studies on cardiopulmonary mechanical uncoupling and multiorgan injury in hemorrhagic shock resuscitation.