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Data · dataset · 2026

Investigation into the effects of fatty acids in the diet of swine on immune response and the gut microbiome

Listed in ZivaHub and Deakin Research Online and DMU Figshare and UCL Research Data Repository — shown once because both records carry DOI 10.17034/32633379.v1

Previously, in-feed antibiotics were used to enhance performance gains and counteract adverse effects of weaning.

Description

However; an EU-wide ban prohibiting the use of antibiotic growth promoters was issued in 2006, prompting the search for safe and innovative alternatives. Studies have indicated that dietary fatty acids can minimise weaning disorders including elevated incidence of enteric disease and immunodepression.

Furthermore, research has indicated that including fatty acids in the porcine diet has a positive effect on performance; increasing growth rate and enhancing feed conversion. It is thought these health and production benefits come from an immunomodulatory role of the fatty acids, however; the mechanisms through which these changes occur are not well understood. <br><br>The aim of this research was to collaborate with local feed industry in order to produce relevant information regarding the use of fatty acids as a swine health supplement and alternative to growth-promoting antibiotics.

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To do this, a combination of in vitro assays and field studies were used to investigate the immunomodulatory and anti-viral properties of a unique blend of fatty acids. Additionally, deep sequencing and metagenomic methods were employed to explicitly explore the influence fatty acid supplementation has on shaping the intestinal microbial community during the weaning period. Results indicate that fatty acids had a positive influence on pif performance, they also acted to initiate and enhance immune response to infection in vitro.

Dietary fatty acids played a role in modifying the intestinal microflora, establishing an environment that favours the growth of commensal species such as Lactobacillus. The fatty acid blend also demonstrated anti-viral activity against porcine rotavirus in vitro.<br>

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Disease 75% · Sequencing 75% · Zoology 71%
Provenance · 4 source records, 15 field assertions
SourceKeyLast seenRaw
ZivaHuboai:figshare.com:article/326333798 d agoJSON v1
Deakin Research Onlineoai:figshare.com:article/326333798 d agoJSON v1
DMU Figshareoai:figshare.com:article/326333798 d agoJSON v1
UCL Research Data Repositoryoai:figshare.com:article/326333798 d agoJSON v1
FieldAssertionExtractorEvidence
concepts[disease].local:disease:diseaseenrichment · zivahub uct ac zakeyword-concept-rules@1.0.0title+description (75%)
concepts[field].anzsrc:group:3109enrichment · zivahub uct ac zataxonomy-embedding@1.1.0title+keywords+description (71%)
concepts[field].local:field:earth-environmentalmapping · dro deakin edu auconnector:dro_deakin_edu_au@1.0.0
concepts[field].local:field:earth-environmentalmapping · figshare dmu ac ukconnector:figshare_dmu_ac_uk@1.0.0
concepts[field].local:field:earth-environmentalmapping · rdr ucl ac ukconnector:rdr_ucl_ac_uk@1.0.0
concepts[field].local:field:earth-environmentalmapping · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
concepts[field].local:field:life-sciencesmapping · dro deakin edu auconnector:dro_deakin_edu_au@1.0.0
concepts[field].local:field:life-sciencesmapping · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
concepts[field].local:field:life-sciencesmapping · figshare dmu ac ukconnector:figshare_dmu_ac_uk@1.0.0
concepts[field].local:field:life-sciencesmapping · rdr ucl ac ukconnector:rdr_ucl_ac_uk@1.0.0
concepts[modality].local:modality:sequencingenrichment · zivahub uct ac zakeyword-concept-rules@1.0.0title+description (75%)
descriptionsource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0/metadata/dc/description
license_textsource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
publication_datesource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
titlesource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0/metadata/dc/title