Data · dataset · 2026
<p>Layered shared-axis evidence and permutation-calibrated OA-OP module correspondence.</p>
Listed in UCL Research Data Repository
<p>(A) Numbers of genes meeting the cumulative direction-consistency, shared-pathway, and module-correspondence criteria.
Description
Layer 3 contained 810 genes occurring in at least one criteria-positive OA-OP module pair. (B) Representative shared biological processes involving immune activation, antigen presentation, extracellular-matrix remodeling, and bone remodeling.
(C) Disease-specific WGCNA blocks and numbers of retained disease-associated modules. Six eligible blocks produced 234 criteria-positive cross-disease module pairs. (D) Numbers of criteria-positive pairs and pairs with empirical FDR < 0.05 in each OA-OP block combination.
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Fifty-three of 464 tested module combinations had empirical FDR < 0.05. The total criteria-positive count was 234 compared with a null mean of 254.83 and a 95% interval of 242–267. OA, osteoarthritis; OP, osteoporosis; FDR, false discovery rate.</p>
Links
Where it is published
- DOI doi.org/10.1371/journal.pone.0359583.g003 ↗
DOI / persistent id · from rdr ucl ac uk
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from rdr ucl ac uk
Topics
Provenance · 1 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| UCL Research Data Repository | oai:figshare.com:article/34048610 | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].anzsrc:field:320211 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Infectious Diseases'] |
| concepts[field].anzsrc:group:3101 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Cell Biology'] |
| concepts[field].anzsrc:group:3105 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Genetics'] |
| concepts[field].anzsrc:group:3204 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Immunology'] |
| concepts[field].local:field:earth-environmental | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| description | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| title | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/title |