Data · dataset · 2026
<p>Low-dose/low-stress exposure does not alter body weight, anxiety-like behavior, or cognition in rats.</p>
Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.1371/journal.pone.0337157.g001
<p>Rats were exposed to low-dose chemical agents under a low-stress protocol for five weeks.
Description
Body weight was monitored during and after exposure. At 4–5 weeks post-exposure, rats received LH-001 or vehicle.
Anxiety-like and cognitive behaviors were assessed beginning 8–9 weeks post-exposure. Data were analyzed using two-way ANOVA unless otherwise indicated. Unless specified, n = 12 per group. <b>(A) Body weight</b> measured weekly during the first six weeks (n = 24/group).
Read the rest (2 more)
No significant differences were observed between groups. <b>(B, C) Open-field test</b>: time spent in the center (B) and total distance traveled (C). <b>(D) Elevated plus maze</b>: percentage of time spent in the open arms. <b>(E, F) Light–dark transition test</b>: latency to enter the dark compartment (E) and percentage of time spent in the light compartment (F) (n = 11–12/group). <b>(G, H) Novelty-suppressed feeding test</b>: food consumption (G) and latency to feed (H) (n = 10–12/group). <b>(I, J) Recognition memory tests</b>: discrimination index for novel object location (I) and novel object recognition (J). <b>(K, L) Barnes maze training</b>: latency to find the escape hole (K) and time spent in the target quadrant (L). <b>(M, N) Barnes maze re-training</b>: latency to locate the new escape hole (M) and time spent in the new target quadrant (N) one week later. <b>(O) Barnes maze memory recall</b>: time spent in the original target quadrant during the re-training probe.
No significant differences were observed between groups in any behavioral measure.</p>
Links
Where it is published
- DOI doi.org/10.1371/journal.pone.0337157.g001 ↗
DOI / persistent id · from zivahub uct ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from zivahub uct ac za
Topics
- From keywords
- Chemistry · Chemistry · Chemistry · Earth & Environmental Science · Earth & Environmental Science · Earth & Environmental Science · Life Sciences · Life Sciences · Life Sciences · Medicine & Health · Medicine & Health · Medicine & Health · Psychology & Behavioral Science · Psychology & Behavioral Science · Psychology & Behavioral Science · Research, science and technology policy · Research, science and technology policy · Research, science and technology policy
Provenance · 3 source records, 23 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ZivaHub | oai:figshare.com:article/34034899 | 9 d ago | JSON v1 |
| Deakin Research Online | oai:figshare.com:article/34034899 | 9 d ago | JSON v1 |
| DMU Figshare | oai:figshare.com:article/34034899 | 9 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].anzsrc:field:440710 | mapping · dro deakin edu au | vocabulary-mapper@1.0.0 | keywords['Science Policy'] |
| concepts[field].anzsrc:field:440710 | mapping · zivahub uct ac za | vocabulary-mapper@1.0.0 | keywords['Science Policy'] |
| concepts[field].anzsrc:field:440710 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Science Policy'] |
| concepts[field].local:field:chemistry | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| description | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/description |
| license | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/rights |
| publication_date | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| title | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/title |