Data · dataset · 2025
Figure 3E Raw data - <b>Increased </b><b><i>in vivo</i></b><b> transduction of AAV-9 cargo in Alport podocytes</b>
Listed in University of Manchester figshare
Description
<p dir="ltr">Raw dataset and analysis for Figure 3E:</p><p dir="ltr"><br></p><p dir="ltr"><b>Figure 3: AAV9-GFP transduction in kidneys of wild type and Alport mice injected at low (6.6x10</b><sup><strong>12</strong></sup><b> vg/kg), medium (3.3x10</b><sup><strong>13</strong></sup><b> vg/kg) and high (1.65x10</b><sup><strong>14</strong></sup><b> vg/kg) dose. </b>In total, 6 (3 WT and 3 Col4a5 KO) 8-week-old mice per group were injected with either AAV9-GFP or saline. <b>E)</b> Colocalization for WT1 and GFP signals was quantified using QuPath and plotted as the percentage of GFP-positive podocytes.
The entirety of glomeruli from 2 whole kidney cross-sections (per genotype/condition) were quantified. Data are presented as mean ± SEM of the values from 3 mice per group and per genotype. P value<0.05 (*), <0.005 (**), <0.0005 (***).</p>
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Where it is published
- DOI doi.org/10.48420/29256509.v1 ↗
DOI / persistent id · from figshare manchester ac uk
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare manchester ac uk
Topics
- From keywords
- Earth & Environmental Science · Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| University of Manchester figshare | oai:figshare.com:article/29256509 | 21 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare manchester ac uk | connector:figshare_manchester_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare manchester ac uk | connector:figshare_manchester_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare manchester ac uk | connector:figshare_manchester_ac_uk@1.0.0 | |
| description | source · figshare manchester ac uk | connector:figshare_manchester_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · figshare manchester ac uk | connector:figshare_manchester_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare manchester ac uk | connector:figshare_manchester_ac_uk@1.0.0 | |
| title | source · figshare manchester ac uk | connector:figshare_manchester_ac_uk@1.0.0 | /metadata/dc/title |