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Data · dataset · 2025

Figure 3E Raw data - <b>Increased </b><b><i>in vivo</i></b><b> transduction of AAV-9 cargo in Alport podocytes</b>

Listed in University of Manchester figshare

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<p dir="ltr">Raw dataset and analysis for Figure 3E:</p><p dir="ltr"><br></p><p dir="ltr"><b>Figure 3: AAV9-GFP transduction in kidneys of wild type and Alport mice injected at low (6.6x10</b><sup><strong>12</strong></sup><b> vg/kg), medium (3.3x10</b><sup><strong>13</strong></sup><b> vg/kg) and high (1.65x10</b><sup><strong>14</strong></sup><b> vg/kg) dose. </b>In total, 6 (3 WT and 3 Col4a5 KO) 8-week-old mice per group were injected with either AAV9-GFP or saline. <b>E)</b> Colocalization for WT1 and GFP signals was quantified using QuPath and plotted as the percentage of GFP-positive podocytes.

The entirety of glomeruli from 2 whole kidney cross-sections (per genotype/condition) were quantified. Data are presented as mean ± SEM of the values from 3 mice per group and per genotype. P value<0.05 (*), <0.005 (**), <0.0005 (***).</p>

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