Data · dataset · 2024
Experimental Data on hIgG Capture Using High-Gradient Magnetic Separation
Listed in Teesside University Research Data Repository
This dataset contains the experimental used in our study on modeling high-gradient magnetic separation (HGMS) for human immunoglobulin G (hIgG) purification.
Description
The data supports the development and validation of mechanistic models that predict magnetic particle (MP) behavior, pH dynamics, and hIgG elution. Key datasets include: 1.
Dynamic Light Scattering (DLS) Data: Measurement of MP size distribution and hydrodynamic diameters under varying conditions. 2. hIgG Quantification Data: Data from high-performance liquid chromatography (HPLC) and UV-absorbance methods for determining hIgG concentration throughout the HGMS process. 3. Isotherm Measurements: Small-scale adsorption and desorption isotherms to determine Langmuir binding parameters. 4. Online Monitoring Data: Data from in-line sensors capturing pH, UV-absorbance, conductivity, and MP concentration dynamics during the RS-HGMS process. 5.
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Particle Size Measurements and TEM Images: Characterization of synthesized magnetic particles, including morphology, magnetization properties, and surface characterization. 6. Process Run Logs: Data logs of RS-HGMS process runs, capturing real-time data and validating model predictions against experimental outcomes.
Links
Where it is published
- DOI doi.org/10.17632/wbgvh6prf8.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Earth & Environmental Science
- Inferred from text
- Image 65%
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/wbgvh6prf8.1 | 13 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[modality].local:modality:image | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (65%) |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |