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Data · dataset · 2013

STAT6 turnover

Listed in DataCite

Decay of Stat6 activation in Ttc7-fsn B cells.

Description

Purified splenic B cells were stimulated with IL-4 for 30 minutes, washed 3X and allowed to rest for 15 or 30 minutes, then stained for Stat6 (red) and the nucleus (green) and imaged with confocal microscopy using a 60x objective. Co-localization of Stat6 with nucleus, denoting activation, is yellow.

Ttc7fsn cells show a similar trend to WT cells at both time points, indicating they have the inherent ability to downregulate Stat6 activation when IL-4 stimulus is removed.

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Stated by source
Clinical medicine
Inferred from text
Microscopy 75%
Provenance · 1 source records, 10 field assertions
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DataCite10.6084/m9.figshare.628069.v112 d agoJSON v1
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concepts[modality].local:modality:microscopyenrichment · DataCitekeyword-concept-rules@1.0.0title+description (75%)
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