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Data · collection · 2016

The reaction of N -isocyaniminotriphenylphosphorane (NICITPP) with some of cyclic ketones and a primary amine in the presence of 3-phenyl-2-propynoic acid

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The 1:1 imine intermediate generated by the addition of a primary amine to a cyclic ketone is trapped by N -isocyaniminotriphenylphosphorane in the presence of 3-phenyl-2-propynoic acid and the corresponding iminophosphorane intermediate was formed.

Description

Disubstituted 1,3,4-oxadiazole derivatives are formed via intramolecular aza -Wittig reaction of the iminophosphorane intermediate. The reactions were completed in neutral conditions at room temperature (18–26°C).

The disubstituted 1,3,4-oxadiazole derivatives were produced in excellent yields.

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Cancer

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Provenance · 1 source records, 12 field assertions
SourceKeyLast seenRaw
DataCite10.6084/m9.figshare.c.314458312 d agoJSON v1
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access_levelsource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
concepts[disease].local:disease:cancermapping · DataCitevocabulary-mapper@1.0.0keywords['Cancer']
concepts[field].fos:biological-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:chemical-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:health-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:physical-sciencessource · DataCiteconnector:datacite@1.0.0
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