Data · dataset · 2024
Screening dataset of food components that inhibit transcriptional activity of FOXO1
Listed in Teesside University Research Data Repository
List of food-derived and natural compounds and their values of reporter activity as FOXO1-transcriptional inhibitors.
Description
Vehicle alone serves as the reference value (set as 100). Data are expressed as mean ± SE (No.1-404: N = 3, No. 405-524: N = 2).
Statistical analyses were performed using the Student's two-tailed unpaired t-test. ***P < 0.001, **P < 0.01, *P < 0.05 compared with the samples in the presence of vehicle alone. HEK293T cells were transfected with GAL4-FOXO1 or GAL4-FOXO3a, (UAS)4-Luc and phRL-TK Luc. Each compound was added and incubated for 20 h and luciferase assay was performed.
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Final concentrations: 1 nM, 10 nM, 100 nM, 1 µM, 10 µM. Data are expressed as mean ± SE (N = 4). Statistical analyses were performed using 1-way analysis of variance (ANOVA) with Dunnett’s post-hoc test. ***P < 0.001, **P < 0.01, *P < 0.05 compared with the samples in the presence of vehicle alone.
Links
Where it is published
- DOI doi.org/10.17632/tgn8xwdr8v.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Social Science
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/tgn8xwdr8v.1 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |