Data · dataset · 2024
The relationship between the microbiome and posttraumatic stress disorder: a protocol for a scoping review
Listed in IISH Dataverse
Posttraumatic Stress Disorder, or PTSD, is a significant health challenge affecting an extensive demographic worldwide.
Description
Despite the availability of various treatments, their effectiveness varies widely, underlining the necessity to understand the mechanisms behind the disorder. An emerging area of exploration is the influence of the human microbiome, the full complement of microbes within us, on PTSD.
Several studies have correlated microbiome imbalances or dysbiosis with mental health disorders, implying potential implications for PTSD via the gut-brain axis, a two-way communication system between our brain and gut. Still, the precise dynamics of this interaction and the extent of its therapeutic potential remain not fully elucidated. A scoping review will provide a comprehensive look at current research on the microbiome-PTSD interplay, shedding light on potential treatment avenues and areas needing additional exploration.
Read the rest (2 more)
A comprehensive literature search will be conducted, using the databases Medline, Embase and PsychINFO. We will concentrate on original data from studies published in the English language. Both human participants diagnosed with PTSD and preclinical studies using rodent models of PTSD will be included.
Outcomes of interest will encompass changes in microbiome composition and diversity, measures of the gut-brain axis, and intervention-related metrics.
Links
Where it is published
- Dataverse dataset page dataverse.nl/dataset.xhtml?persistentId=doi%3A10.34894%2FH4Y9QS ↗
landing page · from datasets iisg amsterdam
- DOI doi.org/10.34894/h4y9qs ↗
DOI / persistent id · from datasets iisg amsterdam
Catalogue records · 1
- Dataverse API dataverse.nl/api/datasets/:persistentId/?persistentId=doi%3A10.34894%2FH4Y9… ↗
metadata API · from datasets iisg amsterdam
Topics
- Stated by source
- Medicine, Health and Life Sciences
- From keywords
- Life Sciences · Medicine & Health
- Inferred from text
- Epidemiology 68%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| IISH Dataverse | doi:10.34894/H4Y9QS | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].anzsrc:group:4202 | enrichment · datasets iisg amsterdam | taxonomy-embedding@1.1.0 | title+keywords+description (68%) |
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 | /subjects |
| created_date | source · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 | |
| description | source · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 | /description |
| publication_date | source · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 | |
| title | source · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 | /name |
| updated_date | source · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 | |
| version_label | source · datasets iisg amsterdam | connector:datasets_iisg_amsterdam@1.0.0 |