Omics · study · 2026
Stem cells from human exfoliated deciduous teeth as a potent cell therapy for refractory osteonecrosis
Listed in NCBI GEO
RNA sequencing was performed to compare gene expression profiles between SHED and BMSCs in a rat model of radiation-induced tibial osteonecrosis.
Description
SHED demonstrated enhanced secretion of angiogenic and chemotactic factors and promoted bone regeneration in vivo, whereas BMSCs showed limited effects. These results suggest that SHED may represent a promising therapeutic strategy for refractory osteonecrosis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE329nnn/GSE329471 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE329471 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1459304 ncbi.nlm.nih.gov/bioproject/PRJNA1459304 ↗
project · from NCBI GEO
- PubMed 42613987 pubmed.ncbi.nlm.nih.gov/42613987 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE329471 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |