IS THE EFFECT OF HOMOEOPATHIC MEDICINE DIFFERENT FROM THE EFFECT OF PLACEBO IN HEALTHY INDIVIDUALS? – A RANDOMIZED, BLINDED, CONTROLLED, THREE ARMED HOMOEOPATHIC PATHOGENETIC TRIAL ON ELECTRO-PHOTONIC IMAGE CHANGES.

This study takes up the challenge to re-evaluate the efficacy of Belladonna in homoeopathic pathogenetic trial in the molecular and ultra-molecular doses.

Method

Randomised, blinded, placebo-controlled three-armed (Belladonna6C, Belladonna200C and Placebo) parallel study (n = 150) conducted in National Institute of Homoeopathy, India. The study design was framed as a four-week protocol consisting of Pre-Intervention period, Intervention Period, Post Intervention period for each participant. Primary and Secondary Outcome Measures are Twelve parameters of Electro Photonic Imaging [EPI] technique and Q-Form-02 (30 items, Likert scale questionnaire) respectively.

Result: The analysis showed a statistically significant difference in eight parameters (P-value <0.05,) out of twelve parameters and the Form Coefficient parameter (P-value <0.001) revealed the effect of placebo during the run-in phase. The questionnaire Q-Form-02 analysis revealed a significant difference among the three groups. The post hoc analysis showed the number of symptoms and the scores among groups depicted the trend: Belladonna 6C > Belladonna 200C > Placebo.

Conclusion: We may conclude that the Electro Photonic Emissions from the human body may serve as a parameter to differentiate the placebo effect from the Homoeopathic medicine effect in the Homoeopathic Pathogenetic Trial [Trial Registration: CTRI/ 2018/03/012290].