Data · dataset · 2025
The role of the WNT5A protein in neoplasms
Listed in REDU - Unicamp Institutional Research Data Repository
Characterizing the tumor microenvironment (TME) is vital for understanding the intricate cellular crosstalk within tumors and for identifying critical immunological markers.
Description
Given the TME's contribution to neoplasm development and progression, a comprehensive analysis can significantly advance cancer diagnosis, prognosis, and therapeutic interventions. Dysregulation of WNT signaling, notably WNT5A, is a key driver of tumorigenesis in multiple cancers.
WNT5A, an evolutionarily conserved protein, displays context-dependent oncogenic or tumor-suppressive activities through modulation of non-canonical pathways, affecting cell growth, migration, and invasion. Therefore, understanding the role of this marker in different neoplasms, particularly hematological malignancies, is crucial for developing targeted therapies and improving patient outcomes.
Links
Where it is published
- Dataverse dataset page redu.unicamp.br/dataset.xhtml?persistentId=doi%3A10.25824%2Fredu%2FXYCRWT ↗
landing page · from redu unicamp br
- DOI doi.org/10.25824/redu/xycrwt ↗
DOI / persistent id · from redu unicamp br
Catalogue records · 1
- Dataverse API redu.unicamp.br/api/datasets/:persistentId/?persistentId=doi%3A10.25824%2Fredu… ↗
metadata API · from redu unicamp br
Topics
- Stated by source
- Medicine, Health and Life Sciences
- From keywords
- Life Sciences · Medicine & Health
- Inferred from text
- Cancer 75% · Predictive and prognostic markers 75%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| REDU - Unicamp Institutional Research Data Repository | doi:10.25824/redu/XYCRWT | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[disease].local:disease:cancer | enrichment · redu unicamp br | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:field:321109 | enrichment · redu unicamp br | taxonomy-embedding@1.1.0 | title+keywords+description (75%) |
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /subjects |
| created_date | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | |
| description | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /description |
| publication_date | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | |
| title | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /name |
| updated_date | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | |
| version_label | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 |