Investigation and evaluation of anti-inflammatory effects of medicinal plants

The majority of inflammatory responses contribute to eliminating the infective pathogens, removing damaged cells and forming new tissue. However, when inflammatory reactions become excessive, the healing process may be concurrently inhibited, resulting in further disorders that are difficult and expensive to treat.

Medicinal plant species have been utilised in traditional medicines as treatments for multiple symptoms associated with inflammatory responses, providing new ideas for solving inflammation-related diseases. This study aims to evaluate the anti-inflammatory capabilities of medicinal plant species and explore their possible therapeutic applications in managing excessive inflammation. <br>Medicinal plant species were selected base on their application in traditional medicine for inflammation-related ailments, and 14 extract samples of them were initially screened for their pro- and anti-inflammatory effects using the interferon regulatory factor (IRF) and the tumour necrosis factor (TNF) pathways on A549 human lung epithelial cell line and RAW 264.7 murine macrophage cell line.