Data · dataset · 2014
A novel 2-bp indel within Krüppel-like factor 15 gene ( KLF15 ) and its associations with chicken growth and carcass traits
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1.
Description
The Krüppel-like factor (KLF) family of zinc-finger transcription factors plays a critical role in cell differentiation, phenotypic modulation and physiologic function. KLF15 has been proposed to regulate adipogenesis and gluconeogenesis.
The objective of this study was to establish the association between KLF15 gene polymorphism and chicken growth and carcass traits.2. An F 2 resource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken KLF15 gene. A 2-bp indel mutation (G13781_13782del/insAG) within intron 2 was detected, and a polymerase chain reaction–restriction fragment length polymorphism method was developed to genotype the F 2 individuals.3.
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Association analysis showed that the Single Nucleotide Polymorphisms (SNP) was significantly associated with chicken growth and carcass traits. The chickens with the insAG/insAG genotype generally had a significantly higher body weight and size than other genotypes. Gene expression for each genotype showed that birds carrying insAG/insAG had a higher expression level than the other genotypes.4.
The results suggested that this polymorphic site may serve as a useful target for marker assisted selection of chicken growth and carcass traits.
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- Repository landing page tandf.figshare.com/articles/dataset/A_novel_2_bp_indel_within_Kr_ppel_like_factor… ↗
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- DOI doi.org/10.6084/m9.figshare.1116232 ↗
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Documentation and papers
- Creative Commons Attribution 4.0 International creativecommons.org/licenses/by/4.0/legalcode ↗
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- IsSupplementTo 10.1080/00071668.2014.921886 doi.org/10.1080/00071668.2014.921886 ↗
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Topics
- Stated by source
- Biological sciences
- From keywords
- Life Sciences
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DataCite | 10.6084/m9.figshare.1116232 | 12 d ago | JSON v1 |
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| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Biological Sciences'] |
| created_date | source · DataCite | connector:datacite@1.0.0 | |
| description | source · DataCite | connector:datacite@1.0.0 | /data/attributes/descriptions |
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| publication_date | source · DataCite | connector:datacite@1.0.0 | /data/attributes/dates |
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