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Data · dataset · 2026

Prophylactic Effects of Chlorogenic Acid Against Cyclophosphamide-Induced Kidney and Bladder Damage in Rats

Listed in Teesside University Research Data Repository

This dataset contains the raw data underlying the study "Prophylactic Effects of Chlorogenic Acid Against Cyclophosphamide-Induced Kidney and Bladder Damage in Rats".

Description

Eighteen male Sprague-Dawley rats (250–300 g) were allocated to three groups (n = 6 per group): a control group (CG), a cyclophosphamide group (CPG; single intraperitoneal dose of 150 mg/kg on day 7), and a cyclophosphamide plus chlorogenic acid group (CP+CGAG; 100 mg/kg/day chlorogenic acid orally on days 1–7 followed by the same cyclophosphamide dose on day 7).

The file contains individual animal values for body weight (days 1 and 8), right kidney and bladder weights, kidney histopathological scores (tubular degeneration, glomerular degeneration, oedema-haemorrhage), bladder damage score, apoptotic indices of both tissues determined by TUNEL, plasma blood urea nitrogen and creatinine, and oxidative stress and inflammatory markers (MDA, TOS, TAS, OSI, SOD, CAT, GSH, TNF-α, MPO) measured in kidney and bladder homogenates.

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Group definitions, scoring criteria, units and ethical approval details are given in the README sheet of the file

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Where it is published

Catalogue records · 1

Topics

Provenance · 1 source records, 11 field assertions
SourceKeyLast seenRaw
Teesside University Research Data Repositoryoai:data.mendeley.com/kcksfzbdpv.110 d agoJSON v1
FieldAssertionExtractorEvidence
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concepts[field].local:field:earth-environmentalmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:engineeringmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:humanitiesmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:life-sciencesmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:social-sciencemapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
descriptionsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/description
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