Pathological and prognostic data of IgA nephropathy

Despite the global prevalence of IgA nephropathy and the recognition of multiple classification systems—namely the Oxford, Lee, and Hass classifications—there remains limited understanding of their applicability and reliability in diverse populations, including the ethnic minorities present in Xinjiang.

Through a retrospective analysis of clinical and pathological data from 408 patients diagnosed with IgA nephropathy, we examined the relationships between different pathological classifications and key clinical indicators such as estimated glomerular filtration rate, serum creatinine, hemoglobin levels, and more. Our findings reveal significant variability in pathological manifestations, with the Oxford classification demonstrating strong correlations with clinical outcomes, while the Lee classification appeared more sensitive in evaluating disease severity compared to the Hass classification.