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Data · dataset · 2015

Synthesis and Antifungal Activity of Novel Quinazolin-4(3 H )-one Derivatives

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A novel group of 6-iodoquinazolin-4( 3H )-one derivatives was prepared starting from 6-iodo-2-ethoxy-4 H -3,1-benzoxazin-4-one (3) via action of various nitrogen nucleophiles such as primary and secondary amines, hydrazine hydrate, and its derivatives.

Description

The 3-amino-2-hydrazinyl-6-iodoquinazolin-4( 3H )-one (15) was used as a key starting material to prepare new heterocyclic compounds. The structures of all synthesized compounds were inferred from the infrared, mass spectral, and 1 H NMR spectral data as well as elemental analysis.

The fungicidal activities of the target compounds were preliminarily evaluated.

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DataCite10.6084/m9.figshare.149549512 d agoJSON v1
DataCite10.6084/m9.figshare.1495495.v412 d agoJSON v1
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