Omics · study · 2026
Candida albicans adapts to toxic levels of the quorum sensing molecule farnesol through cell wall remodeling
Listed in NCBI GEO
In this study, we discover that Candida albicans tolerates farnesol by actively remodeling its cell wall to generate a thicker, less permeable cell wall.
Description
Using RNA seq, we found that C. albicans cells respond to exogenous farnesol by mounting a stress response that involves the upregulation of genes involved in drug efflux, protein folding, redox homeostasis,and cell wall assembly.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE192nnn/GSE192686 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE192686 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA792608 ncbi.nlm.nih.gov/bioproject/PRJNA792608 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
Provenance · 1 source records, 6 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE192686 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |