<p>Targeting SVCV G palmitoylation with a peptide inhibitor.</p>

The different residues are shown in red. CPPtat, CPP from HIV-1 Tat protein. <b>(B)</b> ZF4 cells were transfected with SVCV G for 6 h and then were incubated of CPPtat-GS1 and CPPtat-GS2 for 18 <b>h.</b> IP-ABE detection of palmitoylation of SVCV G in ZF4 cells. <b>(C)</b> ZF4 cells were transfected with SVCV G for 6 h and then were incubated of CPPtat-GS1 and CPPtat-GS2 for 18 <b>h.</b> Then, the cells were analyzed for SVCV G expression. <b>(D-E)</b> ZF4 cells were infected with SVCV G for 6 h and then were incubated of CPPtat-GS1 and CPPtat-GS2 for 18 <b>h.</b> Cell samples and supernatant were collected 24 h after infection.

The viral RNA abundance was detected using qRT-PCR. SVCV titers were measured by Viral plaque assay. <b>(F-G)</b> ZF4 cells were infected with SVCV for 6 h and then were incubated with different concentrations of CPPtat-GS1 for 18 <b>h.</b> Cell samples and supernatant were collected 24 h after infection. The viral RNA abundance was detected using qRT-PCR.