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Data · dataset · 2025

Mateus-Tique et al, Cancer Cell, 2026 - Armored macrophage-targeted CAR T cells reset and reprogram the tumor microenvironment and control metastatic cancer growth

Listed in Teesside University Research Data Repository

This dataset contains Xenium spatial transcriptomics profiles from tumor-bearing mouse omentum samples generated in Mateus-Tique et al., Cancer Cell, 2026.

Description

Tumors were treated with either control therapy or IL12.aFOLR2.CART, and tissues were harvested 10 days post-treatment. Spatial in situ gene expression was measured using the Xenium In Situ v1 chemistry (10x Genomics) with a custom gene panel designed and quality-controlled in collaboration with the 10x Genomics panel design team.

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Cancer 75%
Provenance · 1 source records, 11 field assertions
SourceKeyLast seenRaw
Teesside University Research Data Repositoryoai:data.mendeley.com/kn6tf3nmgm.17 d agoJSON v1
FieldAssertionExtractorEvidence
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concepts[disease].local:disease:cancerenrichment · researchdata tees ac ukkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:earth-environmentalmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:engineeringmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:humanitiesmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:life-sciencesmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:social-sciencemapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
descriptionsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/description
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