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Data · dataset · 2016

Development and study of wound healing activity of an ayurvedic formulation

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The effect of prepared Ayurvedic formulation was evaluated on excision and incision wound models in rats.

Description

The wound-healing activity was assessed by the rate of period of epithelialization and skin-breaking strength. Histologicalstudy of the granulation tissue was carried out to know the extent of collagen formation in the wound tissue.

TheAyurvedic formulation prepared was then promoted for wound-healing activity in two wound models. The treatedanimals showed significant reduction in the wound area up to (P<0.001) and faster rate of epithialisation (23.17±0.54).In an incision wound model, formulation treated animals demonstrated significant skin-breaking strength up to420.33±5.92. Histological studies of the tissue obtained from the formulation treated group revealed that the activitywas more significant in this group.

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Our present study reveals that the Ayurvedic formulation posses potent woundhealing activity, which could be a good choice of remedy for wound healing but less potent than standard Nitrofurazone.

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Medicine & Health

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Provenance · 1 source records, 14 field assertions
SourceKeyLast seenRaw
DataCite10.6084/m9.figshare.3381286.v111 d agoJSON v1
FieldAssertionExtractorEvidence
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concepts[field].fos:biological-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:clinical-medicinesource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:health-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:medical-biotechnologysource · DataCiteconnector:datacite@1.0.0
concepts[field].local:field:medicine-healthmapping · DataCitevocabulary-mapper@1.0.0keywords['Medicine']
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