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Data · dataset · 2026

<p>The WD40 domain of VprBP binds DDB1, which exhibits a dynamic BPB domain.</p>

Listed in ZivaHub and Deakin Research Online and DMU Figshare and UCL Research Data Repository — shown once because both records carry DOI 10.1371/journal.ppat.1014610.g003

<p><b>(A)</b> Interactions between VprBP and DDB1.

Description

The DDB1 BPA and BPC domains are shown in surface representation and colored by electrostatic potential (red, negative; white, neutral; blue, positive). The H-box of the VprBP WD40 domain (green) and the linker between LisH domain and WD40 domain (yellow) are shown as ribbons.

The detailed contact interfaces are zoomed in to highlight key residues involved in the interactions. <b>(B)</b> Interactions between the VprBP ARM-like and DDB1 BPC domains. The ARM-like, LisH, and BPC domains are colored yellow, orange, and cyan, respectively. The zoomed-in views highlight the interfacial residues, which are labeled and shown as sticks. <b>(C)</b> Conformational flexibility of the DDB1 BPB domain.

Read the rest (2 more)

Left, overall structure of DDB1 (BPA, pink, BPB, green, BPC, cyan) in the DDB1-VprBP complex. Right, ribbon diagrams showing the dynamic conformations of the DDB1 BPB domain (green). The tilt angles represent the deviation of the BPB domain pseudo-sevenfold axis relative to the z axis.

The cut-in plane, anchored at the centroid of the BPB domain, was generated with the first two eigenvectors of the domain. Red arrows indicate the direction of the pseudo-sevenfold axis. The ribbons localized to one side of the plane, which are involved in CUL4A recruitment, are colored light green.</p>

Links

Where it is published

Catalogue records · 1

Topics

Provenance · 4 source records, 37 field assertions
SourceKeyLast seenRaw
ZivaHuboai:figshare.com:article/3404793210 d agoJSON v1
Deakin Research Onlineoai:figshare.com:article/3404793210 d agoJSON v1
DMU Figshareoai:figshare.com:article/3404793210 d agoJSON v1
UCL Research Data Repositoryoai:figshare.com:article/3404793210 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
concepts[field].anzsrc:field:310706mapping · zivahub uct ac zavocabulary-mapper@1.0.0keywords['Virology']
concepts[field].anzsrc:field:310706mapping · rdr ucl ac ukvocabulary-mapper@1.0.0keywords['Virology']
concepts[field].anzsrc:field:310706mapping · figshare dmu ac ukvocabulary-mapper@1.0.0keywords['Virology']
concepts[field].anzsrc:field:310706mapping · dro deakin edu auvocabulary-mapper@1.0.0keywords['Virology']
concepts[field].anzsrc:field:320211mapping · dro deakin edu auvocabulary-mapper@1.0.0keywords['Infectious Diseases']
concepts[field].anzsrc:field:320211mapping · zivahub uct ac zavocabulary-mapper@1.0.0keywords['Infectious Diseases']
concepts[field].anzsrc:field:320211mapping · figshare dmu ac ukvocabulary-mapper@1.0.0keywords['Infectious Diseases']
concepts[field].anzsrc:field:320211mapping · rdr ucl ac ukvocabulary-mapper@1.0.0keywords['Infectious Diseases']
concepts[field].anzsrc:group:3101mapping · dro deakin edu auvocabulary-mapper@1.0.0keywords['Cell Biology']
concepts[field].anzsrc:group:3101mapping · zivahub uct ac zavocabulary-mapper@1.0.0keywords['Cell Biology']
concepts[field].anzsrc:group:3101mapping · rdr ucl ac ukvocabulary-mapper@1.0.0keywords['Cell Biology']
concepts[field].anzsrc:group:3101mapping · figshare dmu ac ukvocabulary-mapper@1.0.0keywords['Cell Biology']
concepts[field].anzsrc:group:3104mapping · zivahub uct ac zavocabulary-mapper@1.0.0keywords['Evolutionary Biology']
concepts[field].anzsrc:group:3104mapping · dro deakin edu auvocabulary-mapper@1.0.0keywords['Evolutionary Biology']
concepts[field].anzsrc:group:3104mapping · figshare dmu ac ukvocabulary-mapper@1.0.0keywords['Evolutionary Biology']
concepts[field].anzsrc:group:3104mapping · rdr ucl ac ukvocabulary-mapper@1.0.0keywords['Evolutionary Biology']
concepts[field].anzsrc:group:3108mapping · zivahub uct ac zavocabulary-mapper@1.0.0keywords['Plant Biology']
concepts[field].anzsrc:group:3108mapping · rdr ucl ac ukvocabulary-mapper@1.0.0keywords['Plant Biology']
concepts[field].anzsrc:group:3108mapping · dro deakin edu auvocabulary-mapper@1.0.0keywords['Plant Biology']
concepts[field].anzsrc:group:3108mapping · figshare dmu ac ukvocabulary-mapper@1.0.0keywords['Plant Biology']
concepts[field].local:field:earth-environmentalmapping · dro deakin edu auconnector:dro_deakin_edu_au@1.0.0
concepts[field].local:field:earth-environmentalmapping · figshare dmu ac ukconnector:figshare_dmu_ac_uk@1.0.0
concepts[field].local:field:earth-environmentalmapping · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
concepts[field].local:field:earth-environmentalmapping · rdr ucl ac ukconnector:rdr_ucl_ac_uk@1.0.0
concepts[field].local:field:life-sciencesmapping · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
concepts[field].local:field:life-sciencesmapping · figshare dmu ac ukconnector:figshare_dmu_ac_uk@1.0.0
concepts[field].local:field:life-sciencesmapping · dro deakin edu auconnector:dro_deakin_edu_au@1.0.0
concepts[field].local:field:life-sciencesmapping · rdr ucl ac ukconnector:rdr_ucl_ac_uk@1.0.0
concepts[field].local:field:medicine-healthmapping · dro deakin edu auconnector:dro_deakin_edu_au@1.0.0
concepts[field].local:field:medicine-healthmapping · rdr ucl ac ukconnector:rdr_ucl_ac_uk@1.0.0
concepts[field].local:field:medicine-healthmapping · figshare dmu ac ukconnector:figshare_dmu_ac_uk@1.0.0
concepts[field].local:field:medicine-healthmapping · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
descriptionsource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0/metadata/dc/description
licensesource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0/metadata/dc/rights
publication_datesource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0
titlesource · zivahub uct ac zaconnector:zivahub_uct_ac_za@1.0.0/metadata/dc/title