Table 2_Individual factors associated with arterial and limb occlusion pressure in blood flow restriction: a scoping review of predictors and measurement methods.docx

After duplicate removal and screening, 17 studies met the eligibility criteria. Fifteen examined individual characteristics in relation to occlusion-pressure outcomes, whereas two examined baseline participant characteristics in relation to subsequent morphological or functional responses to BFR. Limb circumference and resting blood pressure were the most commonly examined factors and showed the most consistent associations with AOP/LOP.

Evidence for sex and limb composition was more variable. Cuff width, body position, inflation procedures, and measurement devices also affected the conditions under which AOP/LOP was determined, although these were considered methodological factors rather than individual characteristics.</p>Conclusions<p>Limb size and blood pressure appear to be the individual characteristics most consistently related to AOP/LOP, but substantial methodological heterogeneity makes comparisons across studies difficult.

There is still little evidence showing whether individual characteristics influence physiological, functional, efficacy, or safety outcomes once BFR is applied. Future studies should combine individualized determination of AOP with prespecified interaction, stratified, or predictive analyses to establish whether specific participant characteristics meaningfully influence subsequent responses to BFR.</p>