Dataset for <b>Ultrasensitive chiral detection by nonlinear chiroptics in spiral plasmonic metastructures surpasses linear limits</b>

Conventional methods rely on tedious chromatographic techniques with expensive chiral columns. This work introduces a breakthrough in ultrasensitive chiral detection by combining nonlinear optics and tailored chiral plasmonics.

We fabricate spiral gold metastructures that provide strong enhancements of both electric and superchiral near fields, which simultaneously optimize both the nonlinear conversion efficiency and dissymmetry factor, thereby generating a prominent nonlinear chiroptic response to chiral molecules. The resulting change of circularly polarized second-harmonic generation (ΔCP_SHG) demonstrates remarkable sensitivity to chiral adsorbates, achieving a record-low detection limit of ~11 pM and an outstanding figure of merit of 3260 per micromolar.