Data · dataset · 2026
Young people with perinatally acquired human immunodeficiency viruses (HIV)
Listed in UP Research Data Repository
<p dir="ltr">This mixed-methods study examines long-term treatment outcomes and adherence experiences among young people with perinatally acquired HIV receiving antiretroviral therapy (ART) in rural South Africa.
Description
Quantitative data from TIER.Net (n=583) were used to assess viral suppression, immunological recovery, and retention in care, while qualitative interviews explored barriers and facilitators to lifelong adherence.
Viral suppression improved with ART duration, exceeding 80% after 11 years, alongside significant CD4 recovery, although outcomes varied by clinical stage at initiation and clinic of care. Retention was generally high but inconsistent across facilities. Qualitative findings indicate that adherence is shaped by delayed disclosure, psychosocial burden, food insecurity, transport barriers, and health system constraints, with missed doses reflecting routine disruptions rather than intentional non-adherence.
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Family support, healthcare worker engagement, and future aspirations emerged as key motivators. The findings highlight the need for integrated, youth-friendly interventions to support sustained ART adherence.</p>
Links
Where it is published
- DOI doi.org/10.25403/upresearchdata.32086359.v1 ↗
DOI / persistent id · from researchdata up ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from researchdata up ac za
Topics
Provenance · 1 source records, 13 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| UP Research Data Repository | oai:figshare.com:article/32086359 | 19 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| concepts[field].anzsrc:field:420305 | mapping · researchdata up ac za | vocabulary-mapper@1.0.0 | keywords['Health and community services'] |
| concepts[field].anzsrc:field:420307 | mapping · researchdata up ac za | vocabulary-mapper@1.0.0 | keywords['Health counselling'] |
| concepts[field].anzsrc:field:420310 | mapping · researchdata up ac za | vocabulary-mapper@1.0.0 | keywords['Health surveillance'] |
| concepts[field].anzsrc:field:420311 | mapping · researchdata up ac za | vocabulary-mapper@1.0.0 | keywords['Health systems'] |
| concepts[field].anzsrc:field:420321 | mapping · researchdata up ac za | vocabulary-mapper@1.0.0 | keywords['Rural and remote health services'] |
| concepts[field].local:field:earth-environmental | mapping · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| concepts[field].local:field:humanities | mapping · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| description | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | /metadata/dc/description |
| license | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| title | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | /metadata/dc/title |