Data for Genome reduction is associated with bacterial pathogenicity across different scales of temporal and ecological divergence - between species core gene alignments

Moreover, other typical correlates of genome reduction in endosymbionts (reduced metabolic capacity, reduced GC content, and the transient expansion of non-functional elements) are not consistently observed in pathogens. Together, our results indicate that genome reduction is a predictive marker of pathogenicity in bacteria.<br><br>Data record consists of raw data in .fasta format. For each genus containing at least one pathogen and one non-pathogen, we downloaded all available complete genomes (see Table S2).

(Draft genomes were excluded because we observed that they varied substantially in length for a few species.) We then used Phylosift (Darling et al. 2014) to align 37 single copy orthologs identified as universal to all bacteria. Concatenated alignments of these loci were checked and corrected by eye.