Data · dataset · 2021
Lipidomic profiling reveals lipid regulation to a novel LSD1 inhibitor treatment
Listed in Teesside University Research Data Repository
LSD1 is lysine specific demethylase 1 which plays an important role in tumor metabolism.
Description
ZY0511 is a novel LSD1 inhibitor, systematic analyses of metabolic alterations during ZY0511 treatment will uncover the role of LSD1 implicated in cancer progression. We utilize untargeted tandem mass spectrometry for quantitative lipidomic profiling of HCT116 and Hela cells after ZY0511 treatment for 48 hours.
We detected the changes of lipid metabolites in positive and negative ion modes respectively. The experiment was divided into two groups, the control group and the treatment group, each group contains 6 repeats. The levels of lipids and metabolites are presented in the attached excel file.
Links
Where it is published
- DOI doi.org/10.17632/vjm2z4vd9j.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Earth & Environmental Science
- Inferred from text
- Cancer 75% · Mass spectrometry 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/vjm2z4vd9j.1 | 17 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[modality].local:modality:mass-spectrometry | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |