Supplementary file 1_Instrumented gait characteristics and short-term changes after CAREN training in ischemic stroke: a pilot study.docx

Background<p>Hemiplegic gait disturbance after ischemic stroke severely impairs patients’ mobility; however, existing tools still have limitations in both comprehensive evaluation and routine clinical application.</p>Methods<p>This study enrolled 15 patients with ischemic stroke and 15 healthy controls, and collected gait parameters using the CAREN system. Among these participants, 5 patients completed a 5-day continuous training regimen and participated in a longitudinal before-after comparison analysis.</p>Results<p>Baseline measures revealed pathological gait patterns.

Post-intervention, step width, stride symmetry, and moment profiles showed short-term improvement trends.</p>Conclusion<p>The CAREN system can objectively quantify gait abnormalities in stroke patients and capture short-term change trends, providing a reproducible instrumental gait assessment framework. This study is exploratory in nature, its independent efficacy requires validation through large-sample randomized controlled trials.</p>Clinical Trial Registration<p>chictr.org.cn, identifier ChiCTR2600129541.</p>