Phenotyping data for rice lines edited in the resistance gene against rice yellow mottle disease, rymv1, obtained from the Kitaake variety

Its interaction with the viral VPg protein is essential for infection, and disruptive mutations in eIFiso4G1 are associated with resistance.

While naturally occuring resistance alleles are predominantly found in the African cultivated species Oryza glaberrima, their use in breeding programs is limited by interspecific sterility barriers with the widely cultivated O. sativa. CRISPR-Cas9 technology offers new oppportunities to introduce targeted mutations in elite genotypes, already enabling the generation of knockout (KO) or insertion-deletion (Indel) mutations in susceptibility genes involved in several plant-virus interactions.