Omics · study · 2026
Transcriptomic Response of Escherichia coli strains ECOR53 & LRPF007 to Formaldehyde Stress
Listed in NCBI GEO
This study examines the transcriptomic response of Escherichia coli strains ECOR53 & LRPF007 to formaldehyde (FA) stress using RNA sequencing.
Description
Strains were grown in rich medium (GT) and exposed to defined concentrations of FA. RNA was collected at two key time points: initial stress (early exposure phase) and recovery (after adaptation to FA).
The dataset includes raw FASTQ files, read count matrices, normalized CPM values, and differential expression results. These data reveal strain-specific transcriptional programs and potential detoxification mechanisms, offering insight into how E. coli adapts to formaldehyde toxicity at the molecular level.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305181 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305181 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1303989 ncbi.nlm.nih.gov/bioproject/PRJNA1303989 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE305181 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |