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Data · dataset · 2026

Image 1_Predictive value of the monocyte-to-albumin ratio at admission for 30-day mortality in elderly patients with spontaneous intracerebral hemorrhage: a retrospective analysis.jpeg

Listed in ZivaHub and Deakin Research Online — shown once because both records carry DOI 10.3389/fneur.2026.1948936.s001

Background<p>The monocyte-to-albumin ratio (MAR) integrates systemic inflammation and nutritional status and has been proposed as a predictor of mortality after spontaneous intracerebral hemorrhage (sICH).

Description

However, independent validation in an exclusively elderly cohort remains limited. We aimed to evaluate the association between admission MAR and 30-day mortality in patients aged ≥65 years with sICH.</p>Methods<p>This single-center retrospective study included 206 consecutive elderly patients with acute sICH.

MAR was calculated as monocyte count (×10<sup>9</sup>/L) divided by serum albumin (g/L). The primary outcome was 30-day all-cause mortality. Optimal MAR cutoff was determined by Youden’s index.

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Kaplan–Meier and multivariable Cox regression analyses were performed.</p>Results<p>30-day mortality was 38.8%. MAR was significantly higher in non-survivors (0.022 vs. 0.016, p < 0.001). The optimal cutoff was 0.021 (AUC 0.648, 95% CI 0.572–0.724), providing sensitivity of 57.5% and specificity of 68.3%.

MAR performance was comparable to the neutrophil-to-lymphocyte ratio (AUC 0.643) and systemic inflammatory response index (AUC 0.637). After adjustment, MAR > 0.021 was independently associated with 30-day mortality (adjusted HR 2.41, 95% CI 1.51–3.85, p < 0.001). In a sensitivity analysis using the ICH score as the primary severity covariate, MAR remained independently associated with mortality (adjusted HR 2.02, 95% CI 1.25–3.26, p = 0.004).</p>Conclusion<p>Admission MAR is independently associated with 30-day mortality in elderly sICH patients, although its discriminative ability is limited (AUC 0.648).

As a simple, routinely available parameter, MAR may serve as a supplementary—not standalone—bedside risk stratification tool.</p>

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Image 75%
Provenance · 2 source records, 16 field assertions
SourceKeyLast seenRaw
ZivaHuboai:figshare.com:article/340298406 d agoJSON v1
Deakin Research Onlineoai:figshare.com:article/340298406 d agoJSON v1
FieldAssertionExtractorEvidence
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concepts[field].anzsrc:field:320905mapping · zivahub uct ac zavocabulary-mapper@1.0.0keywords['Neurology and Neuromuscular Diseases']
concepts[field].anzsrc:field:320905mapping · dro deakin edu auvocabulary-mapper@1.0.0keywords['Neurology and Neuromuscular Diseases']
concepts[field].anzsrc:field:440304mapping · dro deakin edu auvocabulary-mapper@1.0.0keywords['mortality']
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