Proteome profiling of home-sampled dried blood spots reveals proteins of SARS-CoV-2 infections

The DBS originated from donors who provided self-sampling blood using a sampling kit (Capitainer AB). The studies were conducted in the general population in Stockholm and Gothenburg (Sweden) during the COVID-19 pandemic in the spring of 2020 and 2021: - Levels of circulating antibodies were determined in the 2021 study by multi-analyte serology using the Luminex platform.

Serology data from the 2020 studies have been deposited in a previous submission (figshare.scilifelab.se/articles/dataset/Multianalyte_serology_in_home-sampled_blood_enables_an_unbiased_assessment_of_the_immune_response_against_SARS-CoV-2/14555520) . All data sets have been processed and normalized using a linear model described in the publication (doi.org/10.1038/s41467-021-23893-4) of the previous submission. - Levels of circulating proteins were determined by proximity extension assays using three Target96 panels from the Olink platform.