Research data for <b>Paired sequencing of IgA-bound bacteria</b>

<p dir="ltr">All bioinformatics outputs related to "Paired sequencing of IgA-bound bacteria reveals widespread associations between adaptive immunity and gut microbiome gene expression" which are required to recreate the statistical analysis in the manuscript.</p><p dir="ltr">Data were generated from IgA-sorted (FACS) gut microbiota of IgMi mice, which produce monoclonal IgA. Positive (IgA-bound) and negative (IgA-unbound) bacterial fractions were subjected to paired metagenomic and metatranscriptomic sequencing.

Full details of the MAG assembly pipeline and bioinformatics processing are available in the manuscript and at <a href="github.com/SauersALogan/PIg-Seq" target="_blank">SauersALogan/PIg-Seq</a>. </p><p dir="ltr">This deposit contains the following files:</p><ol><li>subsampled_dna_abundance.csv — Abundance of each bin from metagenomic sequencing after subsampling reads to equal depth across samples.</li><li>subsampled_rna_activity.csv — Abundance of each bin from metatranscriptomic sequencing after subsampling reads to equal depth across samples.</li><li>DNA_gene_count_controlled_subsampled.csv — Count of each gene from metagenomic sequencing after subsampling reads to equal depth across samples.