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Data · dataset · 2026

Spatial transcriptomics data

Listed in UP Research Data Repository

<p dir="ltr">This dataset contains AlphaSpatial-predicted cell-level gene expression and spatial coordinates for two breast tissue sections, 187 cases from the Yale HER2-status cohort and 81 cases from the Yale trastuzumab-response cohort.

Description

The archive comprises 270 AnnData files containing 14,594,148 valid cell predictions, together with an ROI mapping table. Each file provides untransformed predicted gene counts, gene identifiers, cell coordinates and available ROI and inference-quality metadata.

The mapping table links Yale ROIs to their source slides and annotation geometries. These data support analyses of stromal organization, HER2-associated molecular and spatial patterns, and treatment-response-associated microenvironments. Expression values are model predictions rather than experimentally measured transcript counts.

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Original histological images and model weights are not included.</p>

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Image 65% · Tabular 65%
Provenance · 1 source records, 13 field assertions
SourceKeyLast seenRaw
UP Research Data Repositoryoai:figshare.com:article/340600144 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0
concepts[field].anzsrc:field:310201mapping · researchdata up ac zavocabulary-mapper@1.0.0keywords['Bioinformatic methods development']
concepts[field].local:field:earth-environmentalmapping · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0
concepts[field].local:field:engineeringmapping · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0
concepts[field].local:field:humanitiesmapping · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0
concepts[field].local:field:life-sciencesmapping · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0
concepts[field].local:field:social-sciencemapping · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0
concepts[modality].local:modality:imageenrichment · researchdata up ac zakeyword-concept-rules@1.0.0title+description (65%)
concepts[modality].local:modality:tabularenrichment · researchdata up ac zakeyword-concept-rules@1.0.0title+description (65%)
descriptionsource · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0/metadata/dc/description
licensesource · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0/metadata/dc/rights
publication_datesource · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0
titlesource · researchdata up ac zaconnector:researchdata_up_ac_za@1.0.0/metadata/dc/title