Aging-related psoriasis combined with heart failure dataset

Using the keyword "Heart Failure," we retrieved HF-related gene expression datasets and selected GSE8331, GSE21610, and GSE76701 as the training set, with GSE16499 as the test set.

Single-cell in silicoknockdown analysis was performed using the PSO dataset GSE20201 and the HF dataset GSE298023.After excluding irrelevant samples, the PSO training set comprised 49 samples, including 35 PSO cases and 14 healthy controls; the PSO test set comprised 170 samples, including 85 PSO cases and 85 healthy controls; and the PSO single-cell dataset included 14 samples, with 7 PSO cases and 7 healthy controls.