Data · dataset · 2021
Figure 7
Listed in Borealis and Agri-environmental Research Data Dataverse — shown once because both records carry DOI 10.5683/sp2/f3kqcv
BMK-DKO cells expressing CMcl-1, transfected with VBH3 proteins treated with BH3 mimetics.
Description
Data displayed in Figure 7a-d was generated from combining results of 3 screens: 1) mim1_Mcl1_screen {Rep1_20180906, Rep2_20180907, Rep3_20180908, Rep4_20180909} 2) mim2_Mcl1_screen {Rep1_20190408, Rep2_20190410, Rep3_20190411, Rep4_20190412} 3) Mcl1_ABT199_screen {Rep1_20191024, Rep2_20191025, Rep3_20191026, Rep4_20191027} Figure 7e-f was generated from BH3 swap screen {Rep1_20200821, Rep2_20200827, Rep3_20200902, Rep4_20200904} -For each screen, see "Master Platemap" for screen design as well as data generated in qF3 analysis step 8_CombineBinnedReps: Here are, "combined_WellID_binnedReps_.csv" data files, that were fit to determine live cell Kds.
Exported result from fitting these data is also included in, "CombinedBinnedReps_Results.xlsx". -Figure 7a-c shows the average of controls (VBH3 proteins and corresponding collisional control: VBH3-4E) included in each of these screens. (See "Summarized_CMcl1_ Results.xlsx").
Links
Where it is published
- Dataverse dataset page borealisdata.ca/dataset.xhtml?persistentId=doi%3A10.5683%2FSP2%2FF3KQCV ↗
landing page · from borealisdata ca
- DOI doi.org/10.5683/sp2/f3kqcv ↗
DOI / persistent id · from borealisdata ca
Catalogue records · 1
- Dataverse API borealisdata.ca/api/datasets/:persistentId/?persistentId=doi%3A10.5683%2FSP2%2… ↗
metadata API · from borealisdata ca
Topics
Provenance · 2 source records, 19 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Borealis | doi:10.5683/SP2/F3KQCV | 11 d ago | JSON v1 |
| Agri-environmental Research Data Dataverse | doi:10.5683/SP2/F3KQCV | 9 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].dataverse_subject:other | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].dataverse_subject:other | source · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:chemistry | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:computer-science-ai | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:earth-environmental | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:economics-finance | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:engineering | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:humanities | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:mathematics-statistics | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:ocean-atmospheric | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:social-science | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| created_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| description | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /description |
| publication_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| title | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /name |
| updated_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| version_label | source · borealisdata ca | connector:borealisdata_ca@1.0.0 |