Data · dataset · 2020
RPmirDIP Predictions of ~6 Million miRNA-Gene Pairs
Listed in Borealis and Agri-environmental Research Data Dataverse — shown once because both records carry DOI 10.5683/sp2/ld8jkj
The RPmirDIP and RPmirDIP* predictors were used to re-score all available miRNA-mRNA pairs from the mirDIP database to identify novel putative interactions.
Description
The ~30 million pairs from the mirDIP database were re-scored using the RPmirDIP(*) method(s). Only those pairs with a Difference of Scores (DoS), defined as RPmirDIP(*)-mirDIP, with a value greater than 0.5 were published as these comprise the set of most likely candidate interactors for subsequent experimental validation.
Of this set of ~6 million pairs, the data were divided into subsets based on a cutoff percentile (top 1%, top 5%, top 10%, top 33%, and bottom 66%). These data are presented in two sorted formats. The first is sorted on the Difference of Scores (DoS, RPmirDIP(*)-mirDIP) to identify pairs exhibiting the greatest augmentation of score over mirDIP due to the application of Reciprocal Perspective (RP).
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The second is sorted on the RPmirDIP(*) score to identify those pairs that RP is most confident in, regardless of the augmentation over mirDIP. Both formats support the exploration of potentially novel miRNA-mRNA interactions warranting subsequent wet laboratory validation.
Note
To avoid data duplication, when selecting the top percentile of pairs (say top 10%), you must also select the top percentile files above that level (i.e. top 5% and top 1% files). For convenience, a single file containing all predictions is made available.
Links
Where it is published
- Dataverse dataset page borealisdata.ca/dataset.xhtml?persistentId=doi%3A10.5683%2FSP2%2FLD8JKJ ↗
landing page · from borealisdata ca
- DOI doi.org/10.5683/sp2/ld8jkj ↗
DOI / persistent id · from borealisdata ca
Catalogue records · 1
- Dataverse API borealisdata.ca/api/datasets/:persistentId/?persistentId=doi%3A10.5683%2FSP2%2… ↗
metadata API · from borealisdata ca
Topics
- Stated by source
- Computer and Information Science · Computer and Information Science · Engineering · Engineering · Medicine, Health and Life Sciences · Medicine, Health and Life Sciences
- From keywords
- Chemistry · Computer Science & AI · Earth & Environmental Science · Economics & Finance · Engineering · Engineering · Humanities · Life Sciences · Life Sciences · Mathematics & Statistics · Medicine & Health · Medicine & Health · Ocean & Atmospheric Science · Social Science
- Inferred from text
- Bioinformatics and computational biology 68%
Provenance · 2 source records, 27 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Borealis | doi:10.5683/SP2/LD8JKJ | 11 d ago | JSON v1 |
| Agri-environmental Research Data Dataverse | doi:10.5683/SP2/LD8JKJ | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].anzsrc:group:3102 | enrichment · borealisdata ca | taxonomy-embedding@1.0.0 | title+keywords+description (68%) |
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| concepts[field].dataverse_subject:computer-and-information-science | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].dataverse_subject:engineering | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].dataverse_subject:engineering | source · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].local:field:chemistry | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:computer-science-ai | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:earth-environmental | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:economics-finance | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:engineering | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:engineering | mapping · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].local:field:humanities | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].local:field:mathematics-statistics | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:ocean-atmospheric | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| concepts[field].local:field:social-science | mapping · borealisdata ca dataverse | connector:borealisdata_ca_dataverse@1.0.0 | /subjects |
| created_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| description | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /description |
| publication_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| title | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /name |
| updated_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| version_label | source · borealisdata ca | connector:borealisdata_ca@1.0.0 |