MultiFidelity models for coagulation cascade (in MATLAB)

The multi-fidelity strategy leverages the slow dynamics of molecular diffusion in the coagulation cascade to transform the system of N-PDEs that govern the advection-reaction-diffusion process into a system of p-PDEs for the residence time and its (p-1) statistical moments and N-ODEs for the species concentration as functions of the residence time.

The codes provided here consider the same simplified geometry used in Guerrero-Hurtado et al (2023) to test and validate the MuFi model: an idealized 2D aneurism subject to a pulsating flow, with a coagulation cascade model involving N=9 species. The file Readme.txt contains a brief explanation on how to use the different scripts and functions. More details about the geometry of the idealized aneurism, the mathematical foundation of the MuFi model, or the numerical methods employed to integrate the advection-reaction-diffusion equations (the HiFi model) or the residence time (for the MuFi model) can be found in Guerrero-Hurtado et al (2023). | {"references": ["Guerrero-Hurtado, Garcia-Villalba, Gonzalo, Martinez-Legazpi, Kahn, McVeigh, Bermejo, del Alamo and Flores (2023) Efficient multi-fidelity computation of blood coagulation under flow.