Data for Spin-labelled photo-cytotoxic diazido platinum(IV) anticancer complex

Irradiation with blue visible light gave rise to Pt(II) and azidyl as well as nitroxyl radicals. Pt-TEMPO exhibited low toxicity in the dark, but on photoactivation was as active towards human ovarian cancer cells as the clinical photosensitizer chlorpromazine and much more active than the anticancer drug cisplatin under the conditions used.<br><br>5 files of EPR data as described below Simulations.csv EasySpin generated simulation data, no scaling Full simulation parameters in paper ESI Easyspin version 5.0.9 MATLAB version 8.6.0.267246 (R2015b) 3 columns, 1 header row Col 1: Magnetic Field axis, units mT Col 2: Simulation for Pt-TEMPO compound Col 3: Simulation for DMPO-azidyl adduct EPR_data.csv Experimental data loaded from Bruker Binary with EasySpin Saved as comma separated plain text using MATLAB csvrwite Full experimental parameters in paper / ESI 3 columns, 1 header row Header row: Columns labelled by scan number Col 1: Spectrometer recorded magnetic Field converted to mT Col 2-61: Field swept EPR data TimeDependentConcentration.csv Results of fitting spin adduct concentration as in Fig 3c 2 columns, 1 header row Col 1: Scan time from logging software, decimal minutes i.e. 2.5 min = 2 min 30 seconds etc...

Col 2: Spin adduct concentration extracted from fit 09Dec15_#18_X2.par 09Dec15_#18_X2.spc Raw bruker header and binary data files as generated