Table 1_Impact of incremental peritoneal dialysis on long-term nutritional trajectories in end-stage kidney disease: a longitudinal cohort study.docx

However, its long-term effects on nutritional status remain unclear. This study investigated how an initial IPD strategy influences the longitudinal trajectories of the prognostic nutritional index (PNI) in patients with end-stage kidney disease (ESKD).</p>Methods<p>This retrospective study included patients who received peritoneal dialysis (PD) at the Second Hospital of Jilin University between January 2016 and July 2024.

We employed linear mixed-effects models to analyze population-level trends in PNI. Group-based trajectory modeling (GBTM) was utilized to identify patterns of PNI evolution, while multivariable Cox models assessed the relationship between these patterns and all-cause mortality. Additionally, multivariable logistic regression, which included multiple imputation and entropy balancing-derived inverse probability weights (IPW), was used to explore the independent association between the type of dialysis and trajectory membership.</p>Results<p>A total of 311 patients who initiated PD between 2016 and 2024 were included, of whom 230 received full-dose PD and 81 received IPD.