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Data · collection · 2015

A new cytotoxic biflavonoid from the rhizome of Wikstroemia indica

Listed in DataCite

One new chalcone-flavone biflavonoid, 3′-hydroxydaphnodorin A ( 1 ), together with 12 known biflavonoids ( 2 – 13 ), was isolated from the rhizome of Wikstroemia indica .

Description

Their structures were established on the basis of extensive spectroscopic methods. Eight isolated compounds 1 – 3 , 6 , 7 , 9 , 12 and 13 were evaluated for their cytotoxic activities against cancer-derived cell lines Hep3B, HepG2 and CNE2, and 1 was found to possess moderate cytotoxicity against HepG2 and CNE2 cell lines, with IC 50 values of 65.5 ± 11.4 and 53.6 ± 10.1 μM, respectively.

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Provenance · 2 source records, 19 field assertions
SourceKeyLast seenRaw
DataCite10.6084/m9.figshare.c.211657110 d agoJSON v1
DataCite10.6084/m9.figshare.c.2116571.v110 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
concepts[disease].local:disease:cancermapping · DataCitevocabulary-mapper@1.0.0keywords['Cancer']
concepts[disease].local:disease:cancermapping · DataCitevocabulary-mapper@1.0.0keywords['Cancer']
concepts[field].fos:biological-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:biological-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:chemical-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:chemical-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:earth-and-related-environmental-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:earth-and-related-environmental-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:physical-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].fos:physical-sciencessource · DataCiteconnector:datacite@1.0.0
concepts[field].local:field:medicine-healthmapping · DataCitevocabulary-mapper@1.0.0keywords['Medicine']
concepts[field].local:field:medicine-healthmapping · DataCitevocabulary-mapper@1.0.0keywords['Medicine']
created_datesource · DataCiteconnector:datacite@1.0.0
descriptionsource · DataCiteconnector:datacite@1.0.0/data/attributes/descriptions
licensesource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
publication_datesource · DataCiteconnector:datacite@1.0.0/data/attributes/dates
titlesource · DataCiteconnector:datacite@1.0.0/data/attributes/titles/0/title
updated_datesource · DataCiteconnector:datacite@1.0.0