Data · dataset · 2024
Mismatch Repair (MMR) Gene Mutation Carriers Have Favorable Outcome in Colorectal and Endometrial Cancer: A Prospective Cohort Study
Listed in NYCU Dataverse
Simple
Description
Summary
Germline and somatic deficiencies of mismatch repair proteins (MMRd) are related to colorectal and endometrial cancers, but the survival impact in Asian patients remains unclear. We investigated the prevalence and outcomes of patients with germline and/or somatic MMRd. Germline and somatic MMRd were determined by gene sequencing and protein staining of tumor samples, respectively.
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We found that colorectal and endometrial cancer patients with germline MMRd have favorable survival outcomes compared to those without, regardless of somatic MMRd status. These findings highlight the importance of germline genetic testing when tumor MMRd is detected.
Links
Where it is published
- Dataverse dataset page dataverse.lib.nycu.edu.tw/dataset.xhtml?persistentId=doi%3A10.57770%2FKD8SHY ↗
landing page · from dataverse lib nycu edu tw
- DOI doi.org/10.57770/kd8shy ↗
DOI / persistent id · from dataverse lib nycu edu tw
Catalogue records · 1
- Dataverse API dataverse.lib.nycu.edu.tw/api/datasets/:persistentId/?persistentId=doi%3A10.57770%2FKD8S… ↗
metadata API · from dataverse lib nycu edu tw
Topics
- Stated by source
- Medicine, Health and Life Sciences
- From keywords
- Life Sciences · Medicine & Health
- Inferred from text
- Cancer 75% · Longitudinal study 65% · Sequencing 75%
Provenance · 1 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NYCU Dataverse | doi:10.57770/KD8SHY | 15 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[disease].local:disease:cancer | enrichment · dataverse lib nycu edu tw | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 | /subjects |
| concepts[method].local:method:longitudinal-study | enrichment · dataverse lib nycu edu tw | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · dataverse lib nycu edu tw | keyword-concept-rules@1.0.0 | title+description (75%) |
| created_date | source · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 | |
| description | source · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 | /description |
| publication_date | source · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 | |
| title | source · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 | /name |
| updated_date | source · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 | |
| version_label | source · dataverse lib nycu edu tw | connector:dataverse_lib_nycu_edu_tw@1.0.0 |