Data · dataset · 2024
Microbiota-derived anti-cancer natural products database (MANP)
Listed in ScienceDB
Natural products derived from bacteria play a pivotal role in drug discovery and utilization.
Description
In the past few years, there has been significant interest in pharmaceutical research on the anti-cancer activities of bacteria anti-cancer metabolites (BAMs). However, there are only a few open access databases dedicated to BAMs research.
To meet the increasing need for mining and sharing for BAMs-related data resources, this study introduces Microbiota-derived anti-cancer natural products database (MANP), a comprehensive database designed for bacteria anti-cancer natural products based on manually curated data. Currently, MANP contains more than 1000 secondary metabolites with anti-cancer activities, systematic taxonomy and geographical distribution of source bacteria, detailed structure characterization, physico-chemical properties, ADMET information, experimental biological activity data, and accessible literature citations.
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MANP is an integrated platform for the investigation of bacteria secondary metabolites, discovery of lead compounds, and mining data for structure-activity relationships. Researchers can utilize MANP to explore potential anti-cancer agents derived from bacteria and facilitate the development of novel therapeutic interventions. By providing a comprehensive database of bacterial secondary metabolites, MANP database offers a valuable tool for drug discovery and development in the fight against cancer.
Links
Where it is published
- DOI doi.org/10.57760/sciencedb.11925 ↗
DOI / persistent id · from scidb cn
Catalogue records · 1
- OAI-PMH record scidb.cn/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.57760%2… ↗
metadata API · from scidb cn
Topics
- From keywords
- Chemistry · Earth & Environmental Science · Engineering · Humanities · Life Sciences · Medicine & Health · Social Science
- Inferred from text
- Cancer 75% · Organic chemistry 74%
Provenance · 1 source records, 14 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ScienceDB | 10.57760/sciencedb.11925 | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:group:3405 | enrichment · scidb cn | taxonomy-embedding@1.0.0 | title+keywords+description (74%) |
| concepts[field].local:field:chemistry | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:engineering | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:humanities | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:social-science | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| description | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/description |
| license | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/rights |
| publication_date | source · scidb cn | connector:scidb_cn@1.0.0 | |
| title | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/title |