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Data · dataset · 2024

Undetected cancer in clinical prostate biopsies

Listed in Researchdata.se

This dataset comprises digitized benign prostate hematoxilyn and eosin (H&E) biopsies from men with raised prostate-specific antigen (PSA) values.

Description

The biopsies were systematically taken from different locations in the prostate and were not guided by magnetic resonance imaging (MRI). The dataset includes paired samples from patients with comparable age and PSA levels, all initially diagnosed as benign but with different outcomes upon subsequent follow-ups and re-biopsies.

While some patients remained cancer-free during eight years of follow-up, others were diagnosed with prostate cancer within the subsequent 30 months of follow-up. The final processed dataset includes 213 patients from northern Sweden, resulting in a total of 587 H&E prostate needle biopsies. Among these, 125 control patients with 333 biopsies exhibited no cancer development in eight years following the initial diagnosis.

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Conversely, 88 case patients with 254 biopsies were diagnosed with prostate cancer of various ISUP grades within the 30 months following the initial diagnosis. Each case patient is accompanied by one to three control patients, paired for similar age, PSA value and year of diagnosis. Patients were anonymized by assigning random case IDs and MRXS image files were anonymized by using the module in github.com/bgilbert/anonymize-slide.

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Cancer 75% · Image 75% · Imaging 75% · Magnetic resonance imaging 75%
Provenance · 1 source records, 12 field assertions
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Researchdata.seoai:researchdata.se:2024-144/113 d agoJSON v1
FieldAssertionExtractorEvidence
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