ScienceDB2026 · dataset · unknown
Aging-related psoriasis combined with heart failure dataset…Single-cell in silicoknockdown analysis was performed using the PSO dataset GSE20201 and the HF dataset GSE298023.After excluding irrelevant samples, the PSO training set comprised… …49 samples, including 35 PSO cases and 14 healthy controls; the PSO test set comprised 170 samples, including 85 PSO cases and 85 healthy controls; and the PSO single-cell dataset included…
IISH Dataverse2022 · dataset · unknown
GWAS to single cell: Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell-populations and candidate genes for atherosclerosis.…We collected single-cell transcriptomics (scRNA-seq) from atherosclerotic plaques and aimed to identify cell-type-specific expression of disease-associated genes.… …We present an intuitive single-cell transcriptomics driven workflow rooted in human large-scale genetic studies to identify putative candidate genes and affected cells associated with…
IISH Dataverse2022 · dataset · unknown
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics…These are the single-cell RNAseq data from the Athero-Express Biobank Study as used after quality control in the paper referenced below; below the abstract.… …Methods and Results We performed single-cell RNA and single-cell ATAC sequencing on human carotid atherosclerotic plaques to define the cells at play and determine their transcriptomic…
ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset · unknown
Biophysical correlates of base-mediated radiation cardiotoxicity in non-small cell lung cancer…This thesis investigates the base-mediated radiation cardiotoxicity observed in the radical treatment of non-small cell lung cancer (NSCLC).… …The published clinical experience is limited to small, single-centre clinical cohorts, or large, data-mining analyses, and typically include inadequate levels of cardiovascular co-morbidity…
NASA Data Portal2026 · Astronomical catalogue · unknown
Spaceflight induces systemic effects on extracellular matrix and immune system in different age-stages - Heart atria data…To explore molecular changes, we generated a single-cell RNA sequencing dataset, of 216 samples from 28 mouse organs and tissues under spaceflight and control conditions.… …drives age-independent systemic changes, primarily affecting tissue remodeling and alterations in cytoskeleton, membrane and extracellular matrix (ECM), particularly in endothelial cells…
NASA Data Portal2026 · Astronomical catalogue · unknown
Spaceflight induces systemic effects on extracellular matrix and immune system in different age-stages - Heart ventricles data…To explore molecular changes, we generated a single-cell RNA sequencing dataset, of 216 samples from 28 mouse organs and tissues under spaceflight and control conditions.… …drives age-independent systemic changes, primarily affecting tissue remodeling and alterations in cytoskeleton, membrane and extracellular matrix (ECM), particularly in endothelial cells…
LSHTM Data Compass2021 · dataset · unknown
Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans…(Neu) are known to be associated with diseases such as stroke, peripheral arterial disease, and coronary heart disease.… …significant value of (p = 5 × 10−9) in a composite of the WBC subtypes while the Bayesian fine-mapping analysis identified genetic variants that are more causal than the sentinel single-nucleotide…